NFL Lines Week 1: Point Spreads, Moneyline & O/U

Sunday Night Football Predictions

The 2022 NFL season now upon us and we have all the latest Lines for Week 1 right here for you – updated every single day.

Whether you’re looking for point spreads or you are betting straight up, you’ve come to the right place people.

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The real thing gets under way Thursday September 8 at SoFi Stadium when the Super Bowl champion Rams host the Super Bowl favorite Bills – we have a same game parlay for you on that one and some Thursday night football player props.

We have seen pretty significant movement on some of the lines already – Buffalo opened a half-point underdog vs the Rams and is now a two-and-a-half-point favorite.

So let’s check out the lines for a terrific first weekend of NFL action:

Week 1 Lines – Point Spreads

Here are the very latest lines and point spreads for Week 1 – updated September 11, 2022:

Sunday September 11, 2022

New Orleans Saints (-5.5) @ Atlanta Falcons (+5.5) – 1pm ET, FOX

Baltimore Ravens (-6.5) @ New York Jets (+6.5) – 1pm ET, CBS

Cleveland Browns (+0.5) @ Carolina Panthers (-0.5) – 1pm ET, CBS

San Francisco 49ers (-6.5) @ Chicago Bears (+6.5) – 1pm ET, FOX

Philadelphia Eagles (-5) @ Detroit Lions (+5) – 1pm ET, FOX

Pittsburgh Steelers (+7) @ Cincinnati Bengals (-7) – 1pm ET, CBS

Indianapolis Colts (-7) @ Houston Texans (+7) – 1pm ET, CBS

New England Patriots (+3.5) @ Miami Dolphins (-3.5) – 1pm ET, CBS

Jacksonville Jaguars (+3) @ Washington Commanders (-3) – 1pm ET, FOX

Kansas City Chiefs (-6.5) @ Arizona Cardinals (+6.5) – 4.25pm ET, CBS

Green Bay Packers (-1) @ Minnesota Vikings (+1) – 4.25pm ET, FOX

Las Vegas Raiders (+3.5) @ Los Angeles Chargers (-3.5) – 4.25pm ET, CBS

New York Giants (+5.5) @ Tennessee Titans (-5.5) – 4.25pm ET, FOX

Tampa Bay Buccaneers (-2.5) @ Dallas Cowboys (+2.5) – 8.20pm ET, NBC

Monday September 12, 2022

Denver Broncos (-6.5) @ Seattle Seahawks (+6.5) – 8.15pm ET, ESPN/ABC

Week 1 Lines – Moneyline

If you want to bet straight up with no spread on Week 1, here are the early best odds available:

GameRoadHome
New Orleans Saints @ Atlanta Falcons-225+200
Cleveland Browns @ Carolina Panthers-105-107
Baltimore Ravens @ New York Jets-295+250
San Francisco 49ers @ Chicago Bears-280+250
Philadelphia Eagles @ Detroit Lions-215+198
Indianapolis Colts @ Houston Texans-320+275
Pittsburgh Steelers @ Cincinnati Bengals+240-275
Jacksonville Jaguars @ Washington Commanders+135-150
New England Patriots @ Miami Dolphins+160-175
Kansas City Chiefs @ Arizona Cardinals-267+230
Green Bay Packers @ Minnesota Vikings-110+100
Las Vegas Raiders @ Los Angeles Chargers+160-170
New York Giants @ Tennessee Titans+215-240
Tampa Bay Buccaneers @ Dallas Cowboys-140+126
Denver Broncos @ Seattle Seahawks-270+250

Week 1 Lines – Over/Under

Buying or selling total points in a game is one of THE best bets on an NFL Sunday – here are the Week 1 lines:

GameOver/Under
New Orleans Saints @ Atlanta Falcons43
Cleveland Browns @ Carolina Panthers42
Baltimore Ravens @ New York Jets44
San Francisco 49ers @ Chicago Bears40.5
Philadelphia Eagles @ Detroit Lions48.5
Indianapolis Colts @ Houston Texans45.5
Pittsburgh Steelers @ Cincinnati Bengals44.5
Jacksonville Jaguars @ Washington Commanders44
New England Patriots @ Miami Dolphins46
Kansas City Chiefs @ Arizona Cardinals53.5
Green Bay Packers @ Minnesota Vikings47
Las Vegas Raiders @ Los Angeles Chargers52.5
New York Giants @ Tennessee Titans44
Tampa Bay Buccaneers @ Dallas Cowboys50.5
Denver Broncos @ Seattle Seahawks44.5

NFL Week 1 Predictions

You can check out our way too early Week 1 NFL predictions by clicking here.

Our Sunday Night Football Predictions are here.

Our Monday Night Football Predictions are here.

Our Week 1 NFL Parlay Picks are here.

Our Week 1 NFL picks Against The Spread are here.

Our Week 1 NFL Prop Bets are here.

NFL Betting explained

Okay so not all of you are likely experienced bettors, so how about we enlighten you? We’ve put together a full guide on how the odds work, and you can check it out here.

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