NFL Week 5 Lines, Picks, Predictions & Inactives

Joe Burrow Cincinnati Bengals NFL 2021

We are on to a terrific slate of Sunday Week 5 games in the NFL and we have everything you need, including latest lines, odds, picks, predictions, TV details and those all-important inactives.

We have some fantastic matchups in prospect, including a key AFC North matchup with Cincinnati visiting Baltimore and the Dallas Cowboys locking horns with the Super Bowl champion Rams in Los Angeles.

We have the latest lines for you, plus a host of picks and predictions (and some nice signup bonus offers).

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NFL Predictions & Picks for Week 5

We have a ton of picks and predictions for you, and here is how you can get them:

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NFL Week 5 Lines, Start Times & TV Details

Here are the very latest lines and spreads heading into Sunday’s slate:

Week 5

Thursday October 6, 2022

  • Indianapolis Colts 12-9 Denver Broncos (OT) 8:15 PM Prime Video

Sunday October 9, 2022

  • New York Giants (+8) vs Green Bay Packers (-8) (Tottenham) 9:30 AM NFLN
  • Los Angeles Chargers (-2.5) at Cleveland Browns (+2.5)  1:00 PM CBS
  • Houston Texans (+7) at Jacksonville Jaguars (-7) 1:00 PM CBS
  • Atlanta Falcons (+9.5) at Tampa Bay Buccaneers (-9.5) 1:00 PM FOX
  • Pittsburgh Steelers (+14) at Buffalo Bills (-14) 1:00 PM CBS
  • Chicago Bears (+7.5) at Minnesota Vikings (-7.5) 1:00 PM FOX
  • Detroit Lions (+3) at New England Patriots (-3) 1:00 PM FOX
  • Seattle Seahawks (+5.5) at New Orleans Saints (-5.5) 1:00 PM FOX
  • Tennessee Titans (-1.5) at Washington Commanders (+1.5) 1:00 PM CBS
  • Miami Dolphins (-3) at New York Jets (+3) 1:00 PM CBS
  • San Francisco 49ers (-6.5) at Carolina Panthers (+6.5) 4:05 PM CBS
  • Philadelphia Eagles (-5) at Arizona Cardinals (+5) 4:25 PM FOX
  • Dallas Cowboys (+5.5) at Los Angeles Rams (-5.5) 4:25 PM FOX
  • Cincinnati Bengals (+3.5) at Baltimore Ravens (-3.5) 8:20 PM NBC

Monday October 10, 2022

  • Las Vegas Raiders (+7) at Kansas City Chiefs (-7) 8:15 PM ESPN

NB: All lines correct on Friday October 7, 2022

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NFL Week 5 Inactives

If you are betting or playing fantasy, you will need these:

Cincinnati Bengals

  • RB Trayveon Williams
  • OT D’Ante Smith
  • G Jackson Carman
  • CB Cam Taylor-Britt
  • DT Jay Tufele

Baltimore Ravens

  • WR Rashod Batement
  • RB Justice Hill
  • CB Jayln Armour-Davis
  • OLB Justin Houston
  • LB A.J. Klein
  • G Ben Cleveland

San Francisco 49ers

  • RB Marlon Mack
  • DT Arik Armstead
  • DT Javon Kinlaw
  • LT Trent Wiliams
  • RB Ty Davis-Price
  • S Tarvarius Moore
  • TE Tyler Kroft

Carolina Panthers

  • WR Laviska Shenault
  • WR Rashard Higgins
  • CB Stantley Thomas-Oliver
  • S Xavier Woods
  • LB Frankie Luvu
  • OL Cade Mays
  • TE Stephen Sullivan

Philadelphia Eagles

  • K Jake Elliott
  • QB Ian Book
  • CB Avonte Maddox
  • LB Patrick Johnson
  • DE Janarius Robinson
  • T Jordan Mailata

Arizona Cardinals

  • K Matt Prater
  • CB Trayvon Mullen
  • RB Keaontay Ingram
  • LB Jesse Luketa
  • C Rodney Hudson
  • OL Max Garcia
  • DL Rashard Lawrence 

Dallas Cowboys

  • QB Dak Prescott
  • T Jason Peters
  • WR Jalen Tolbert
  • DT Quinton Bohanna
  • S Markquese Bell
  • LB Devin Harper
  • CB Nahshon Wright

Los Angeles Rams

  • CB David Long
  • S Taylor Rapp
  • WR Lance McCutcheon
  • C Brian Allen
  • CB Cobie Durant 
  • QB Bryce Perkins

Pittsburgh Steelers

  • QB Mason Rudolph
  • DB Ahkello Witherspoon
  • S Terrell Edmunds
  • G Kendrick Green
  • WR Gunner Olszewski
  • DT Isaiahh Loudermilk
  • LB Mark Robinson

Buffalo Bills

  • WR Isaiah McKenzie
  • WR Jake Kumerow
  • TE Dawson Knox
  • OL Justin Murray
  • LB Tremaine Edmunds
  • CB Christian Benford
  • S Jordan Poyer

Los Angeles Chargers

  • WR Keenan Allen
  • K Dustin Hopkins
  • QB Easton Stick
  • RB Isaiah Spiller
  • S JT Woods
  • TE Richard Rodgers
  • DT Otito Ogbonnia

Cleveland Browns

  • QB Kellen Mond
  • WR Michael Woods II
  • RB Demetric Felton Jr.
  • T Joe Haeg
  • G Drew Forbes
  • T Chris Hubbard
  • TE Miller Forristall

Houston Texans

  • TE Brevin Jordan 
  • WR Chris Moore
  • DL Jonathan Greenard
  • LB Blake Cashman 
  • DL Thomas Booker
  • OL Austin Deculus
  • DL Demone Harris 

Jacksonville Jaguars

  • WR Kendric Pryor
  • RB Snoop Conner
  • S Tyree Gillespie
  • CB Montaric Brown
  • OLB De’Shaan Dixon
  • DL Folorunso Fatukasi 

Chicago Bears

  • DB Dane Cruikshank
  • DL Kingsley Jonathan
  • DB Jaylon Johnson
  • TE Jake Tonges

Minnesota Vikings

  • CB Andrew Booth Jr.
  • OLB Luiji Vilain
  • G/C Chris Reed
  • T Vederian Lowe
  • WR Jalen Nailor
  • DL Esezi Otomewo
  • DL Khyiris Tonga

Detroit Lions

  • CB Amani Oruwariye
  • WR DJ Chark
  • RB D’Andre Swift
  • DL Charles Harris
  • DL John Cominsky
  • S JuJu Hughes
  • T Matt Nelson

New England Patriots

  • DT Lawrence Guy
  • DE DaMarcus Mitchell
  • QB Mac Jones
  • TE Jonnu Smith
  • DB Joshuah Bledsoe
  • CB Shaun Wade
  • RB Pierre Strong

Seattle Seahawks

  • WR Marquise Goodwin
  • CB Sidney Jones IV
  • CB Justin Coleman
  • S Teez Tabor
  • T Jake Curhan
  • WR Dareke Young

New Orleans Saints

  • WR Jarvis Landry
  • S Marcus Maye
  • WR Michael Thomas
  • G Calvin Throckmorton
  • DE Payton Turner
  • TE Nick Vannett
  • QB Jameis Winston

Miami Dolphins

  • QB Tua Tagovailoa
  • RB Salvon Ahmed
  • WR Erik Ezukanma
  • TE Hunter Long
  • CB Xavien Howard
  • LB Trey Flowers

New York Jets

  • QB Mike White
  • WR Denzel Mims
  • TE Lawrence Cager
  • LB Quincy Williams
  • CB Bryce Hall
  • S Tony Adams

Atlanta Falcons

  • TE Kyle Pitts
  • LB DeAngelo Malone
  • LB Nick Kwiatkoski
  • OL Chuma Edoga
  • WR Jared Bernhardt

Tampa Bay Buccaneers

  • QB Kyle Trask
  • WR Julio Jones
  • WR Breshad Perriman
  • TE Cameron Brate
  • S Logan Ryan
  • DL Akiem Hicks

Tennessee Titans

  • DB Ugo Amadi
  • S Amani Hooker
  • LB Zach Cunningham
  • LB Joe Jones
  • OLB Bud Dupree
  • G Nate Davis
  • OLB Ola Adeniyi

Washington Commanders

  • WR Jahan Dotson
  • QB Sam Howell
  • S Percy Butler
  • CB Tariq Castro-Fields
  • LB David Mayo
  • T Sam Cosmi
  • TE Logan Thomas

New York Giants

  • QB Tyrod Taylor
  • WR Kenny Golladay
  • WR Wan’Dale Robinson
  • WR Kadarius Toney
  • OLB Azeez Ojulari
  • CB Cor’Dale Flott
  • DL Leonard Williams

Green Bay Packers

  • WR Samori Toure
  • OT Rasheed Walker
  • OL Sean Rhyan
  • DL Jonathan Ford
  • DL Devonte Wyatt

Indianapolis Colts

  • QB Sam Ehlinger
  • RB Jonathan Taylor
  • OT Luke Tenuta
  • C Wesley French
  • DE Tyquan Lewis
  • LB Shaquille Leonard
  • S Julian Blackmon

Denver Broncos

  • RB Latavius Murray
  • WR Jalen Virgil
  • OL Quinn Meinerz
  • OLB Jonathon Cooper
  • OLB Aaron Patrick
  • CB Darius Phillips
  • S P.J. Locke